• Sertificēta klīniski diagnostiskā laboratorija

  • Sertificēta klīniski diagnostiskā laboratorija

Rezultātu interpretācija

Interpretation of results

Kinship tests/Determination of paternity – maternity/Interpretation of results

 

What does a negative result mean?

Paternity can be excluded if at least two or more loci of a child's DNA profile show results that are inconsistent with the results of the probable father. In such a case there is no doubt that the tested male is NOT the biological father of the child.

An example of a negative result

DNA regions

(loci)

Probable father's DNA profile

Person Y, Sample No. 99xxxxxxT1

Child's DNA profile

Person B, Sample No. 99xxxxxxB

Mother's DNA profile

Person M, Sample No. 99xxxxxxM

Likelihood of kinship

D8S1179

10

14

14

14

14

16

possible

D21S11

28

29

29

31.5

31.5

33.2

possible

D7S820

6

6

6

11

6

6

not possible

CSF1PO

11

11

12

18

10

18

not possible

D3S1358

14

16

17

18

17

18

not possible

D13S317

10

10

12

12

12

13

not possible

TH01

8.2

8.2

8

9

8

8.2

not possible

D16S539

10

11

12

12

12

15

not possible

D2S1338

20

23

15

17

17

19

not possible

D19S433

14

17

12

13

12

14

not possible

vWA

17

18

16

19

16

18

not possible

TPOX

8

10

8

11

10

11

possible

D18S51

13

15

18

18

17

18

not possible

Amelogenin

x

y

x

x

x

x

female

D5S818

11

11

11

12

12

18

not possible

FGA

21

22

20

23

20

25

not possible

D1S1656

16.3

18

17

18

11

18

not possible

D2S441

10

10

12

12

12

12

not possible

D10S1248

13

16

14

14

12

14

not possible

Penta E

14

15

11

12

12

13

not possible

Penta D

9

13

10

12

10

11

not possible

DYS391

11

 

 

 

 

 

 

D12S391

20

24

17

20

17

18

possible

D22S1045

11

16

11

13

13

15

not possible

CONCLUSIONS

Conclusions made on basis of DNA testing of samples 99xxxxxxT1, 99xxxxxxM and 99xxxxxxB:

  1. The person from whom sample 99xxxxxxB was taken is female.
  2. Likelihood ratio = 0;
  3. Likelihood that the person Y (sample number 99xxxxxxT1) is the biological father of person X (sample No. 99xxxxxxB) is excluded.

 

What does a positive result mean?

Paternity can be confirmed if one of the results in all tested DNA loci of the child matches with that of the probable father, and the other – with the result of the mother. It is very important to note that a positive test result always has a very high statistical probability (usually from 99.99 to over 99.9999999999 %), and not 100 % because there is a possibility that there are also other men in the world whose DNA loci might have the same result as the person being tested.

An example of a positive result

Loci

DNA regions

Probable father's DNA profile

Person Y, Sample No. 98xxxxxxT1

Child's DNA profile

Person B, Sample No. 98xxxxxxB

Mother's DNA profile

Person M, Sample No. 98xxxxxxM

Likelihood of kinship

D8S1179

12

13

11

12

11

16

possible

D21S11

28

29

22.2

29

22.2

30

possible

D7S820

10

10

10

11

11

12

possible

CSF1PO

10

20

10

12

12

13

possible

D3S1358

17

18

15

18

15

19

possible

TH01

5

7

7

9.3

9

9.3

possible

D13S317

10

11

10

11

9

11

possible

D16S539

8

10

8

12

12

12

possible

D2S1338

20

21

20

23

17

23

possible

D19S433

14.2

15

14.2

15

15

15

possible

vWA

17

20

14

17

14

17

possible

TPOX

7

8

8

8

6.3

8

possible

D18S51

13

14

14

15

15

17

possible

Amel

x

y

x

x

x

x

female

D5S818

11

13

11

11

11

11

possible

FGA

19

25

21

25

21

24

possible

D1S1656

13

16.3

12

16.3

12

16.3

possible

D2S441

11

14

13

14

10

13

possible

D10S1248

11

13

11

15

14

15

possible

Penta E

7

15

7

13

7

13

possible

Penta D

13

14

11

14

11

11

possible

DYS319

11

 

 

 

 

 

female

D12S391

16

20

16

18

15

18

possible

D22S1045

15

17

15

17

15

17

possible

CONCLUSIONS

Conclusions made on basis of DNA testing of samples 98xxxxxxT1, 98xxxxxxM and 98xxxxxxB:

  1. The person from whom sample 98xxxxxxB was taken is female.
  2. Likelihood ratio = 668310087854.37;
  3. Likelihood that the person Y (sample No. 98xxxxxxT1) is the biological father of person’s M (sample No. 98xxxxxxM) child (person B) (sample No. 98xxxxxxB) is 99.99999999997104%